PLATELET CARE

Nethika Natural ’s Platelet Care Supplement has been scientifically designed to improve blood platelet count and take care of other symptoms in Dengue. The product contains best quality standardized extracts of Papaya (Carica papaya), Neem (Azadirachta indica), Guduchi (Tinospora cordifolia) and Chirata (Swertia chirata)

Highlights:

• 100% natural or herbal
• Contains best quality standardized plant extracts
• Veg capsules (gelatin-free)
• Contains no chemicals (preservatives, colorants or additives)

Dose: 1 capsule twice a day after meals

Packing: 60 veg capsules

DESCRIPTION

Thrombocytopenia is a condition in which you have a low blood platelet count. Platelets (thrombocytes) are colorless blood cells that help blood clot. Thrombocytopenia might occur as a result of a bone marrow disorder such as leukemia, anemia, viral or bacterial infections or an immune system problem. Or it can be a side effect of taking certain medications. Dangerous internal bleeding can occur when your platelet count falls below 10,000 platelets per microliter. Though rare, severe thrombocytopenia can cause bleeding into the brain, which can be fatal.

Dengue is a fast emerging pandemic-prone viral disease in many parts of the world.The incidence of dengue has increased 30-fold over the last 50 years. A normal person has a platelet count of between 1.5 and 4 lakhs per microlitre of blood. About 80 to 90 percent of patients with dengue will have levels below 1 lakh which can be treated and brought to normal with the help of medicines which boost platelet count, while 10 to 20 per cent of patients will see critically low levels of 20,000 or less. In such cases, they are likely to be admitted to the hospital and receive platelet transfusions to prevent the possibility of internal bleeding.

Additional information

Frequently Asked Questions

What are Platelets and what is their role in health?

Platelets (also called thrombocytes) are colourless blood cells made in the bone marrow along with white and red blood cells. 

Platelets perform an important role in blood clotting. If one of the blood vessels gets damaged, it sends out signals to the platelets. The platelets then rush to the site of damage and form a plug (clot) to fix the damage. This is because when platelets get to the site of the injury, they stick (adhere) to one another. They also send out chemical signals to attract more platelets. The additional platelets pile onto the clot forming plugs in blood vessel injuries and stop bleeding.

What is thrombocytopenia and what are its causes?

A normal human platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Thrombocytopenia is a condition in which the blood platelet count does down below 150,000. This can be caused due to following reasons:

Decreased Platelet Production: Factors that can lead to decreased platelet production include:

• Dehydration, Vitamin B12 or Folic acid deficiency
• Decreased production of thrombopoietin by liver in liver failure
• Leukemia and other cancers
• Some types of anemia
• Systemic bacterial or viral infection
• Viral infections, such as hepatitis C or HIV
• Chemotherapy drugs and radiation therapy
• Heavy alcohol consumption

Increased Breakdown of Platelets: Some conditions can cause the body to use up or destroy platelets faster than they're produced, leading to a shortage of platelets in your bloodstream. Examples of such conditions include:

• Pregnancy
• Dengue fever
• Immune thrombocytopenia. In autoimmune diseases such as lupus and rheumatoid arthritis the body's immune system mistakenly attacks and destroys platelets
• Bacterial infections
• Thrombotic thrombocytopenic purpura.This is a rare condition that occurs when small blood clots suddenly form throughout the body, using up large numbers of platelets.
• Hemolytic uremic syndrome.This rare disorder causes a sharp drop in platelets, destruction of red blood cells and impairs kidney function.
• Certain medications can trigger the immune system and cause it to destroy platelets or can directly suppress the bone marrow. Examples include heparin, quinine, sulfa-containing antibiotics, H2 blockers, and anticonvulsants.

Entrapped Platelets: Cirrhosis of the liver or Gaucher disease can cause enlarged spleen . The enlarged spleen traps platelets and other blood cells and prevents them from circulating in the blood stream reducing their blood count.

What happens if platelet count falls below normal?

A lack of platelets in the body may cause symptoms like:

• Fatigue
• Easy bruising
• Bleeding gums and nose
• Blood in the urine and stool
• Prolonged wound healing or
• Heavy menstrual bleeding.

People with severe thrombocytopenia are at risk for significant internal and external blood loss, or haemorrhage. Dangerous internal bleeding can occur when the platelet count falls below 10,000 platelets per microliter. Though rare, severe thrombocytopenia can cause bleeding into the digestive tract or brain (intercranial hemorrhage) which can be life-threatening.

Why does platelet count reduce in dengue?

Dengue has turned out to be one of the health conditions that can be life-threatening. Dengue fever is a result of a viral infection that is transmitted by mosquitoes. When an infected mosquito bites a human, the dengue virus enters the bloodstream, it binds to platelets and replicates leading to multiplication of infectious virus. The infected platelet cells tend to destroy normal platelets which is one of the major causes for the drop in the platelet count in dengue fever.

Thrombocytopenia is thus a common clinical manifestation in patients with either mild or severe cases of dengue infections. Studies suggest that the low platelet count is one of the major causes of bleeding in these patients. The platelet counts drop below normal level (150,000–450,000 platelets/μL) and may reach as low as <40000 platelets/μL during day 3–7 of fever in many patients. In some cases, patients have to be transfused with platelets to maintain their normal hemostatic activity. Development of thrombocytopenia in dengue patients mainly rests on two events: decreased production of platelets in the bone marrow and/or increased destruction and clearance of platelets from peripheral blood.

What is the medical treatment for increasing platelet count?

Treatment of thrombocytopenia basically includes correcting the underlying cause, which may include discontinuing drugs suspected to cause it or treating underlying infections. 

Other treatments include:

Blood transfusion helps to temporarily increase platelet levels in the blood. Platelets are transfused only if the platelet count is extremely low. (Transfused platelets only last about three days in the circulation.)

Splenectomy or removal of the spleen.

Medications like steroids (prednisone or dexamethasone), immunoglobulins (antibody proteins), and other medications that reduce platelet destruction and stimulate platelet production.

Is blood transfusion advisable or safe in Dengue patients?

Most clinical guidelines recommend that platelet transfusions be given to patients who develop serious hemorrhagic manifestations or have very low platelet counts, platelet counts falling below 10–20 × 10⁹ L⁻¹ without hemorrhage or 50 × 10⁹ L⁻¹ with bleeding or hemorrhage. The efficacy of platelet transfusions is controversial. Studies have shown that there was no significant difference in hemorrhage between patients who received preventive transfusions compared to those who did not. Patients who received transfusion had a higher frequency of pulmonary edema and increased length of hospitalization. Platelet transfusion did not prevent the development of severe bleeding or shorten the time to bleeding cessation and was associated with significant side effects. Thus, according studies, platelet transfusions should not be routinely performed in the management of dengue 

What are the best natural remedies to boost platelet count?

Simple ways to increase blood platelet count are:

• Eating Vitamin K rich foods - Green leafy vegetables like spinach and fenugreek leaves, broccoli and soybean contain Vitamin K which does not directly increase platelet level but plays an important role in blood clotting.
• Eating Fatty Fish- Fish like Salmon, trout and tuna contain high amounts of B12. Low levels of B12 are linked with low platelet counts.
• Eating Folate rich Foods- Folic acid helps increase platelet levels. Thus increasing consumption of folate rich foods like Broccoli, kidney beans and peanuts helps boost platelet count.
• Vitamin C rich foods- Vitamin C rich foods are also helpful in increasing platelet count. These foods include Guava, Kiwi, Orange, Lemon, Strawberries, Pineapple, Peas, Mango and Broccoli.
• Eating Iron rich foods- Consuming iron rich foods like beef liver, tofu, kidney beans, or oysters help boost platelet count.
• Chlorophyll Supplementation- Chlorophyll, which is abundant in green plants, helps in increasing platelet count. So supplementation with Superfoods like Spirulina or Wheatgrass is helpful.
• Papaya- Papaya is the best natural remedy for dengue. Research has shown that supplementation with papaya leaf extract is highly effective in increasing the platelet count of patients suffering from dengue.

How does Nethika Naturals Platelet Care Supplement work?

NETHIKA NATURALS PLATELET CARE SUPPLEMENT has been scientifically designed to improve blood platelet count and take care of other symptoms in Dengue infection. It contains high quality standardized extracts of Papaya (Carica papaya), Neem (Azadirachta indica), Guduchi (Tinospora cordifolia) and Chirata (Swertia chirata)

The overall effects of Ingredients are mentioned below:

• Boost Platelet Count: Papaya, Guduchi and Neem help increase platelet count
• Boost WBC Count: Neem leaves have shown to increase both blood platelets and white blood cell platelet count, two of which are the worst side effects of dengue fever. 
• Prevents Dengue Infection: Nimbin and nimbidin, two compounds present in Neem and Acetogenin, a compound found in papaya leaf help in preventing diseases like malaria and dengue by virtue of their strong anti-malarial and anti-viral properties. They help in arresting the viral replication and hence the infection.
• Helps in Dengue Symptoms: Papaya, Chirata, Neem and Guduchi help in reducing other symptoms of dengue like high fever, skin rash, weakness, headache, joint pain and loss of appetite probably due to their anti-inflammatory and anti-pyretic effects.
• Helps in Complications of Thrombocytopenia: Papaya prevents complication associated with thrombocytopenia
• Helps in Blood Purification: The herbs also help to boost immunity, purify blood and remove toxins from the body

What is the Dose of the product?

The recommended dose is 1 capsule twice a day after meals.

For how long can I use this product?

The product is 100% natural. Its ingredients are safe and so the Supplement can be used for a long period.

Are there any side effects?

Nethika Naturals Platelet Care Supplement is 100% natural and safe. It is made from the best quality standardized extracts sourced from certified vendors who produce the extracts in cGMP, FDA, HALAL and KOSHER approved manufacturing facility. All the individual herbs present in the supplement are reported to be safe with no adverse/side effects.